Human myeloid cell reconstitution is enhanced in BRGS^humanmice. (A) Representative flow cytometric plots of reconstituted human hematopoietic cells in the bone marrow of BRGS^NOD or BRGS^human recipients. The percentages of each lineage are shown as those within the human CD45⁺ population. Numbers indicate the percentages of gated cells. (B) Frequencies of human CD33⁺ myeloid cells (top panels), CD19⁺ B cells (middle panels), and CD3⁺ T cells (bottom panels) in bone marrow at 10 to 12 weeks (left panels) and at 20 to 24 weeks (right panels) after transplantation. The numbers and horizontal lines indicate mean values. *P < .05, **P < .01. n.s., not significant.