Glucocorticoid-responsive T-ALL/T-LBL PDX samples show IL7R/CISH/PIM1 upregulation upon dexamethasone treatment. (A) IL7R mRNA expression levels are shown for 11 PDX spleen samples with and without 100 nM dexamethasone (dex) treatment of 24 hours, in 10% RPMI supplemented with 50 ng/mL IL7. (B) CISH mRNA expression levels are shown for 11 PDX spleen samples with and without 100 nM dexamethasone treatment of 24 hours, in 10% RPMI supplemented with 50 ng/mL IL7. (C) PIM1 mRNA expression levels are shown for 11 PDX spleen samples with and without 100 nM dexamethasone treatment of 24 hours, in 10% RPMI supplemented with 50 ng/mL IL7. *P < .05; **P < .01; ***P < .001; ****P < .0001. ns, non significant.