Linear correlation and nonlinear fit between increasing EFS and decreasing use of health care per month of EFS for all patients. Overall use of health care per month of EFS (A), combined clinic visits, ER visits, hospitalizations, and consultations per month of EFS (B), combined invasive procedures, imaging, and laboratory studies per month of EFS (C), and blood product transfusions per month of EFS (D). (E) Use of health care in patients grouped according to increasing EFS. The decline in use of health care between patients with EFS of 1 to 6 months, >6 to 12 months, and >12 to 18 months was highly statistically significant. (F) Trend of overall use of health care with increasing EFS in patients grouped according to narrow OS ranges. Overall use of health care consisted of the sum of the number of clinic visits, ER visits, hospital admissions, consultations, blood product transfusions, laboratory studies, imaging studies, and invasive procedures. Blood product transfusions included packed red blood cell and platelet transfusions.