Figure 5.
![Gata2 heterozygous loss increases the incidence of EVI1-driven leukemia with high platelets and Mks. (A) PLT counts in the peripheral blood of leukemic 3q21q26-EVI1 (red circle) and 3q21q26-EVI1::Gata2+/gfp (blue square) mice. An orange dotted line represents PLT levels of age-matched WT mice. (B) Percentages of Mks in the bone marrows of leukemic 3q21q26-EVI1 (red circle) and 3q21q26-EVI1::Gata2+/gfp (blue square) mice. (C) Kaplan-Meier survival curves of 3q21q26-EVI1 (High-Mk type leukemia [orange dotted line], Low-Mk type leukemia [red line]), and 3q21q26-EVI1::Gata2+/gfp mice (High-Mk type leukemia [turquoise line] or Low-Mk type leukemia [blue dashed line]). *P < .05 (log-rank test).](https://ash.silverchair-cdn.com/ash/content_public/journal/bloodadvances/4/8/10.1182_bloodadvances.2019000978/1/advancesadv2019000978f5.png?Expires=1724195976&Signature=gonzyyq44um6jk2np1Q-gHpQACZdXN4vGcB8Sm1oNiB04rpdKhiKgjzNQ8n7dKGFcJGobY7yBUhJUCNIvF9iuZpL6jxXxbY8hD0vpWM9poTZg3JgpgfD~yf~DFpqWFAVFd3HcRfr8GQSGGKuO6rNvrWIzgbRJN5VDBHpDkhVo8l6pSAlop7vRbB0LkOIglBWgsbQBwvPJGv7ugRgBOyD3osM2LUOjyVfNYTqx8emRt76RQ68lDs0B8KvKXpHwAGDYMZW5TvJTcenFsNhSU6vlxsHVKsiCMsHCzEK-CTKjoJKa1lfLCoeOCH1Z67oXgKZCczgF43WzVdXJJOmBX1Yjw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Gata2 heterozygous loss increases the incidence of EVI1-driven leukemia with high platelets and Mks. (A) PLT counts in the peripheral blood of leukemic 3q21q26-EVI1 (red circle) and 3q21q26-EVI1::Gata2+/gfp (blue square) mice. An orange dotted line represents PLT levels of age-matched WT mice. (B) Percentages of Mks in the bone marrows of leukemic 3q21q26-EVI1 (red circle) and 3q21q26-EVI1::Gata2+/gfp (blue square) mice. (C) Kaplan-Meier survival curves of 3q21q26-EVI1 (High-Mk type leukemia [orange dotted line], Low-Mk type leukemia [red line]), and 3q21q26-EVI1::Gata2+/gfp mice (High-Mk type leukemia [turquoise line] or Low-Mk type leukemia [blue dashed line]). *P < .05 (log-rank test).