Dynamic of HSPC subsets. (A) Proportion of ISs persisting over time in each IS subset. (B) An alluvial plot showing the changes in the different IS subsets comprising the 768 clones that were present at both m12 and m48. (C) A heat map showing the TOP15 IS clones from multipotent, myeloid-dominant, and T-cell-dominant subsets at m48 for the 4 available points (m12, m36, m48, and m60). Each row represents a unique IS clone, with its closest gene labeled on the right. Integration within the transcription unit is indicated by a star. IS abundance is represented by color-code scale.