Figure 1.
![Study design. (A) Patient cohort of the retrospective derivation study, May 2014 to August 2015 (n = 221 [22 HIPA-positive cases]). (B) Patient cohort of the prospective derivation study, September 2015 to December 2016 (n = 305 [26 HIPA-positive cases]). 1CLIA ≥0.13 U/mL. (C) Standards for the Reporting of Diagnostic Accuracy Studies flowchart of the patient cohort of the prospective validation study, January 2017 to November 2019 (n = 687 [53 HIPA-positive cases]).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/135/14/10.1182_blood.2019002845/2/bloodbld2019002845f1.png?Expires=1723260302&Signature=VEdY5goemqLsL~oi7N~tYSyjHjEcg3Dwb79gIqmBTpGQ~nEQz6pjPGxKL4vkAde3E6RcxHbcgge8qSE0Tq9iD37QAzVjckn6M6ky0bAtXVi-x0f719jfVeU6qKMHlCVuWPkwY-BB~4RRtt-Ypn2kaMaYlK~2ZiNIwTj0kCiJWbpsvQVdmE50JsaN3RM4egxp0f7bI1Yo-0cJO30mDuW3vpZFHSqaqnsYC-662Yn0acAYaXZ5VWZqWu7LbG6QMA32Kvkb1ZB~ahnYxN~0Z9WvUoAmCouUFA4f-1d~-QJ7oZlrnqi0ptSMsf52-U4O8I2Gfj39klVmVaFiZKbQrwzA7Q__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Study design. (A) Patient cohort of the retrospective derivation study, May 2014 to August 2015 (n = 221 [22 HIPA-positive cases]). (B) Patient cohort of the prospective derivation study, September 2015 to December 2016 (n = 305 [26 HIPA-positive cases]). 1CLIA ≥0.13 U/mL. (C) Standards for the Reporting of Diagnostic Accuracy Studies flowchart of the patient cohort of the prospective validation study, January 2017 to November 2019 (n = 687 [53 HIPA-positive cases]).