Survival analysis. (A-B) Kaplan-Meier plot of the OS and PFS of the cohort. (C-D) A significant negative effect is observed on PFS (but not on OS after P value correction) in patients harboring amplification of chr1q (ie, >3 copies). (E-F) No significant effect is observed in patients showing a double-hit of the TP53 locus. (G-H) A trend toward shorter survival is observed in patients with deletion or mutations of the PRDM1 gene in chr6q. For all plots, numbers of patients at risk are shown in tables below the graphs.