Figure 1.
Survival curves of mice with Tet insufficiency. Kaplan-Meier survival curves of ΔT2ΔT3 (Mx1-Cre+Tet2f/fTet3f/f; n = 41); T2ΔT3 (Mx1-Cre+Tet2f/wTet3f/f; n = 51); ΔT2T3 (Mx1-Cre+Tet2f/fTet3f/w; n = 47); T2T3 (Mx1-Cre+Tet2f/wTet3f/w; n = 38); ΔT2 (Mx1-Cre+Tet2f/fTet3wt/wt, n = 61); and ΔT3 (Mx1-Cre+Tet2wt/wtTet3f/f, n = 73) mice. ****P < .0001.

Survival curves of mice with Tet insufficiency. Kaplan-Meier survival curves of ΔT2ΔT3 (Mx1-Cre+Tet2f/fTet3f/f; n = 41); T2ΔT3 (Mx1-Cre+Tet2f/wTet3f/f; n = 51); ΔT2T3 (Mx1-Cre+Tet2f/fTet3f/w; n = 47); T2T3 (Mx1-Cre+Tet2f/wTet3f/w; n = 38); ΔT2 (Mx1-Cre+Tet2f/fTet3wt/wt, n = 61); and ΔT3 (Mx1-Cre+Tet2wt/wtTet3f/f, n = 73) mice. ****P < .0001.

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