Figure 5.
Effect of CTI and SBTI on TG initiated by RBC-MVs in plasma. (A) Effect of CTI (dashed green) and SBTI (hashed gray) on kaolin-initiated (30 µg/mL) TG in MV-free NPP. (B) Effect of CTI (hashed green) and SBTI (gray) on TG initiated by RBC-MVs in NPP. (C) Effect of SBTI (gray) on TG initiated by RBC-MVs in FXII-deficient, MV-free plasma, as compared with XII-deficient plasma alone (hashed dark green). (D) Effect of SBTI (gray) on TG initiated by RBC-MVs in FXI-deficient, MV-free plasma as compared with XI-deficient plasma alone (dashed purple). Data representative of 3 independent experiments. Buffer (blue) was used as the negative control (A-D), and NPP (red) was used as a comparator (B-D). Data are representative of 3 independent experiments.

Effect of CTI and SBTI on TG initiated by RBC-MVs in plasma. (A) Effect of CTI (dashed green) and SBTI (hashed gray) on kaolin-initiated (30 µg/mL) TG in MV-free NPP. (B) Effect of CTI (hashed green) and SBTI (gray) on TG initiated by RBC-MVs in NPP. (C) Effect of SBTI (gray) on TG initiated by RBC-MVs in FXII-deficient, MV-free plasma, as compared with XII-deficient plasma alone (hashed dark green). (D) Effect of SBTI (gray) on TG initiated by RBC-MVs in FXI-deficient, MV-free plasma as compared with XI-deficient plasma alone (dashed purple). Data representative of 3 independent experiments. Buffer (blue) was used as the negative control (A-D), and NPP (red) was used as a comparator (B-D). Data are representative of 3 independent experiments.

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