Correlation between anti-AAV5 NABs and total antibodies. (A) Total anti-AAV5 antibodies were measured by ELISA on plasma samples collected before, during, and after the IA procedure. A significant decrease (*0.0266) was realized between the OD450 before and after the IA procedure using a Friedman test and a Dunn multiple comparison test. (B) A correlation was established by exponential regression between the levels of total and anti-AAV5 NABs just before and throughout the IA procedure (pre IA, cycle 1, 2, 3).