Graft failure. (A) Graft failure by age at transplantation. The 5-year probabilities of graft failure for patients aged ≤6 years, 7 to 15 years, and 16 to 25 years were 8% (6% to 10%), 10% (7% to 12%), and 22% (7% to 34%), respectively. (B) Graft failure by donor type. The 5-year probabilities of graft failure after HLA-matched relative, HLA-mismatched relative, HLA-matched unrelated, and HLA-mismatched unrelated donor transplants were 9% (6% to 11%), 21% (12% to 29%), 6% (3% to 9%), and 11% (5% to 18%), respectively.