Fig. 4.
Regression of AIDS-KS tumors by intraperitoneal injections of IL-13 toxin.
(A) Nude mice were implanted subcutaneously with approximately 30 mg of KS Y-1 tumor mass on day 0. The animals then received injections twice a day with IL-13 toxin on day 4 through 8. The control mice received excipient only. The second cycle of injections was given on day 11 through 15. Each group had 6 animals. (B) KS-imm cells (2 × 106/50 μL) mixed with 100 μL of Matrigel were implanted on day 0 and 5 daily injections began on day 3. The control and treatment groups had 7 and 6 mice, respectively. The arrows indicate the day of injections.
