Deletions of γ gene promoter.

(A) Internal deletions of γ gene promoter. CACCC and stage selector (SSE) sequences were deleted from the γ gene promoter as indicated. (B) Effect of deletion of CACCC box and SSE on γ promoter activation by FKLF-2. Reporter constructs containing a luciferase gene driven by γ gene promoters with internal deletions depicted in Figure 6A were tested in K562 cells.