Fig. 7.
Fig. 7. Localization of IP3 receptors (IP3R) and GAP1IP4BP in platelets. / The plasma membrane preparation (PM) contains the type III receptor, which is surface exposed and is likely to be involved in either Ca++ or Na+ entry (see text). The type II receptor and GAP1IP4BP eluting with the plasma membrane preparation are suggested to link with a plasma membrane cation channel. The intracellular membranes contain the type I and type II receptors involved with Ca++ release from intracellular stores and thapsigargin (TG) sensitive SERCA Ca++ATPases.

Localization of IP3 receptors (IP3R) and GAP1IP4BP in platelets.

The plasma membrane preparation (PM) contains the type III receptor, which is surface exposed and is likely to be involved in either Ca++ or Na+ entry (see text). The type II receptor and GAP1IP4BP eluting with the plasma membrane preparation are suggested to link with a plasma membrane cation channel. The intracellular membranes contain the type I and type II receptors involved with Ca++ release from intracellular stores and thapsigargin (TG) sensitive SERCA Ca++ATPases.

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