CDR3 fragment analysis of T-cell expansions at separate time points, showing (A) BV8 CD4 T-cell expansions of patient three 10 months apart (15% and 29%) and (B) BV2 CD4 T-cell expansions of patient four 4 months apart (50% and 60%), and (C) AV12S1 CD8 T-cell expansion of patient five 2 months apart (41% and 35%). Relevant controls of healthy subjects are shown at the bottom.