Fig. 2.
Fig. 2. Amelioration of mortality (A) and weight loss (B) by KGF following allogeneic BMT with a nonuniformly lethal dose of allogeneic spleen cells. B10.BR recipient mice (n = 8/group) were lethally irradiated (7.5 Gy) on day −1 and infused on day 0 with C57BL/6 BM either without (BM) or with 5 × 106 spleen cells (BMS) as indicated. For (A), (□) BM ± KGF, (▪) BMS + PBS, and (▴) BMS + KGF. For (B), (□) BM + PBS, (▵) BM + KGF, (▪) BMS + PBS, and (▴) BMS + KGF. *.0003 < P < .01 from this point.

Amelioration of mortality (A) and weight loss (B) by KGF following allogeneic BMT with a nonuniformly lethal dose of allogeneic spleen cells. B10.BR recipient mice (n = 8/group) were lethally irradiated (7.5 Gy) on day −1 and infused on day 0 with C57BL/6 BM either without (BM) or with 5 × 106 spleen cells (BMS) as indicated. For (A), (□) BM ± KGF, (▪) BMS + PBS, and (▴) BMS + KGF. For (B), (□) BM + PBS, (▵) BM + KGF, (▪) BMS + PBS, and (▴) BMS + KGF. *.0003 < P < .01 from this point.

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