Fig. 4.
![Fig. 4. Different effects between group I and group II antagonists on [Ca2+]i changes induced by thrombin. Platelets were preincubated with 10 μmol/L of each antagonist and then stimulated with 0.03 U/mL thrombin. (A) None. (B) FK633 (group I). (C) FR169824 (group I). (D) Ro44-9883 (group II). (E) MK383 (group II). AG and Ca2+ indicate aggregation curve and trace of changes in [Ca2+]i, respectively. These results are representative of two separate experiments.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/92/10/10.1182_blood.v92.10.3675/4/blod42238004x.jpeg?Expires=1724258121&Signature=jT7XWKQn6amJvlI6kP2TxWpXqW4cZdCR~dRn~dunX~579Swvld8B6~LCPyYwWChtmD6mL8IIE7KRLtkS0tE-gfEOoq9vrZT0GjHyETrqfnkpESYSrXo9OE7b-GoAOJd0dUuxNbQ6vJ1PUHLT3XXJtzhGvzNM0Aii9T-~mh7QeLJdCeI~LxD3Mu-~imq8gJG43KM3DpRBdOU24mF~6MPvujmwEtL0KLe6yRmJKuqV93n71vjnfgR9HVxc5BUMA4XxzMPKJSiqFnI059BmxAKf5j~sywtpAbOlU~hnD6PpOTNTC3XtPn2n5eSL6NxQXo020klsi3J0kSzaLHTSM~Ipmg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Different effects between group I and group II antagonists on [Ca2+]i changes induced by thrombin. Platelets were preincubated with 10 μmol/L of each antagonist and then stimulated with 0.03 U/mL thrombin. (A) None. (B) FK633 (group I). (C) FR169824 (group I). (D) Ro44-9883 (group II). (E) MK383 (group II). AG and Ca2+ indicate aggregation curve and trace of changes in [Ca2+]i, respectively. These results are representative of two separate experiments.
