Aird Figure 1
Aird Figure 1. (in Warkentin et al). Schematic of interactions between platelets and endothelial cells. / Shown are three endothelial cells, a number of small platelets, and a representative monocyte. Vertical arrows indicate soluble molecules that are released by one cell type and signal in the other. Curved and horizontal arrows indicate platelet-leukocyte cross talk and shear stress, respectively, both of which may impact on the nature of endothelial-platelet interactions. At bottom are platelet and endothelial receptors that have been implicated in mediating interactions between these two cell types. / Abbreviations: PAF, platelet activating factor; ROS, reactive oxygen species; NO, nitric oxide; IL-1, interleukin-1; VEGF, vascular endothelial growth factor; GP, glycoprotein; PECAM-1, platelet endothelial adhesion molecule-1; ICAM-1, intercellular adhesion molecule-1; TSP-1, thrombospondin-1.

(in Warkentin et al). Schematic of interactions between platelets and endothelial cells.

Shown are three endothelial cells, a number of small platelets, and a representative monocyte. Vertical arrows indicate soluble molecules that are released by one cell type and signal in the other. Curved and horizontal arrows indicate platelet-leukocyte cross talk and shear stress, respectively, both of which may impact on the nature of endothelial-platelet interactions. At bottom are platelet and endothelial receptors that have been implicated in mediating interactions between these two cell types.

Abbreviations: PAF, platelet activating factor; ROS, reactive oxygen species; NO, nitric oxide; IL-1, interleukin-1; VEGF, vascular endothelial growth factor; GP, glycoprotein; PECAM-1, platelet endothelial adhesion molecule-1; ICAM-1, intercellular adhesion molecule-1; TSP-1, thrombospondin-1.

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