Figure 7.
Figure 7. Annexin A5—effect of aPL antibody. / (A) An atomic force image of the 2-dimensional crystallization of annexin A5 over a phospholipid bilayer. Each of the circular structures that compose each row is a trimer of annexin A5. The crystal covers nearly 100% of the phospholipid bilayer. / (B) The effects of a monoclonal aPL antibody together with β2GPI on the crystal structure of annexin A5. The aPL-β2GPI results in marked disruptions of the annexin A5 crystal. / Abbreviations: aPL, antiphospholipid; β2GPI, β2-glycoprotein I.

Annexin A5—effect of aPL antibody.

(A) An atomic force image of the 2-dimensional crystallization of annexin A5 over a phospholipid bilayer. Each of the circular structures that compose each row is a trimer of annexin A5. The crystal covers nearly 100% of the phospholipid bilayer.

(B) The effects of a monoclonal aPL antibody together with β2GPI on the crystal structure of annexin A5. The aPL-β2GPI results in marked disruptions of the annexin A5 crystal.

Abbreviations: aPL, antiphospholipid; β2GPI, β2-glycoprotein I.

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