Figure 3.
![Figure 3. Intravenous injection of MSCs ameliorates EAE. MSCs injected at days 3 and 8 after immunization (▪) halt disease severity compared with controls (▵) (P < .05 from day 17 onward). No differences were observed between controls and mice treated at day 24 after immunization (▴) (A). Administration of MSCs at day 10 (▪) or at day 15 (▴) after immunization, after disease onset, ameliorates EAE (P < .05 from day 22 [*] for mice treated at day 10 and from day 30 [§] for mice treated at day 15 compared with controls [▵] by Mann-Whitney U test) (B). Arrows indicate days of MSC injection.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/106/5/10.1182_blood-2005-04-1496/6/zh80170583590003.jpeg?Expires=1724258022&Signature=rjfLv2QN7Okcp1hVLQArUyCCFce3rEtIDmwwKL7nT4GBvAp8E6tja-NQ1aJLT8Odd3QYH3f~PMZ9tAvj7lLBHxO~7vkqKMQ8Qgcyyf98lasrP~1w7HHTEmq-RIZuM2qHcsA~3c4ZqnTVwbAdp-4wnVvgS5rPEv32UV1G3DJ1CEs9q8F4RM0RYKPGTflFYXLY0w4-sbeFKcgD4ae0VaVVFxM5UwcLD3e1J3KeOz8P4sjDlay7fgBvlnXoO~7A8CPblmsQsxZL94I8xyx143nb8njxujeRo6xw-LjSMVrQn8BXObvpnIj2fiuLlo4NiwuE6KeUq7y00TRe5QbLXCXg6g__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Intravenous injection of MSCs ameliorates EAE. MSCs injected at days 3 and 8 after immunization (▪) halt disease severity compared with controls (▵) (P < .05 from day 17 onward). No differences were observed between controls and mice treated at day 24 after immunization (▴) (A). Administration of MSCs at day 10 (▪) or at day 15 (▴) after immunization, after disease onset, ameliorates EAE (P < .05 from day 22 [*] for mice treated at day 10 and from day 30 [§] for mice treated at day 15 compared with controls [▵] by Mann-Whitney U test) (B). Arrows indicate days of MSC injection.
