Figure 2.
Figure 2. Both PE and oxidation are required to observe inhibition of APC activity by anti–β2-GPI. PS/PC and PE/PS/PC vesicles were either not oxidized (▪) or oxidized (▦) in the presence or absence of anti-β2 mAb no. 1522 (120 nM) and APC (0.4 μg/mL) as indicated on the x-axis. Similar results were obtained with the other antibodies. Error bars indicate the SE of 2 or 3 determinations run in duplicate.

Both PE and oxidation are required to observe inhibition of APC activity by anti–β2-GPI. PS/PC and PE/PS/PC vesicles were either not oxidized (▪) or oxidized (▦) in the presence or absence of anti-β2 mAb no. 1522 (120 nM) and APC (0.4 μg/mL) as indicated on the x-axis. Similar results were obtained with the other antibodies. Error bars indicate the SE of 2 or 3 determinations run in duplicate.

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