Structure and mutations of the PIG-A gene.

The coding region is shown in the form of boxes; introns are shown in the form of dashed lines (not drawn to scale). Nucleotide numbers are shown above the exons. Null mutations (frameshift, nonsense and splicing) are indicated above the exons. Missense mutations and in frame deletions are indicated below the exons. Each symbol represents one individual mutation. All mutations are somatic, except for the two shown in green. From reference ¹⁷ .