Illustration of the treatment schema for basic ALL therapy, Berlin-Frankfurt-Munster (BFM) derived therapy which includes basic therapy plus additional agents in induction, consolidation and delayed intensification, and augmented BFM therapy which includes all BFM therapy plus additional vincristine, asparaginase and intravenous methotrexate during times of potential myelosuppression plus a second delayed intensification approximately 10 months into treatment.

Abbreviations: VCR, vincristine; PDN, prednisone; ASP, L-asparaginase; IT, intrathecal; MTX, methotrexate; DNM, daunorubicin; 6MP, 6 mercaptopurine; CPM, cyclophosphamide; Ara-C, cytarabine; XRT, cranial irradiation; DEX, dexamethasone; DOX, doxorubicin.