Comparison of gene expression profiles demarcates clusters with similar and differential gene regulation between mutants. There were 387 genes differentially expressed between WT and clo embryos. The expression responses of these genes were then determined in clo, vlt, mon, bls, and spt mutants, as well as in scl^mo, and hierarchically clustered. Four clusters that matched the predicted expression profiles of the early hematopoietic and vascular genes, of the erythroid, myeloid, and vascular lineages, and an additional cluster with genes up-regulated in clo and scl^mo embryos, are highlighted. Fold changes are shown as log2 (mutant/WT, or morphant/uninjected). Blue and yellow boxes indicate decreased and increased gene expression, respectively, in mutant compared with WT (morphant compared with uninjected) embryos.