Figure 4.
![Figure 4. R-etodolac synergistically enhances Dex-induced cytotoxicity against MM cells. MM.1S cells were cultured for 24 hours with control media (□) and with 0.5 μM Dex (▦) or 1.0 μM Dex (▪) in the presence or absence of R-etodolac (0.15-0.6 mM). Cell growth was assessed by [3H]-thymidine uptake (A) and MTT assays (B). CPM indicates counts per minute. (C) Dose dependency for inhibition of proliferation of MM1.S cells at 24 hours was analyzed by MTT assays, after culture with 18 to 600 μM R-etodolac alone (♦), 0.06 to 2 μM Dex alone (□), or both (▴). Data represent mean (± SD) of quadruplicate cultures.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/106/2/10.1182_blood-2005-02-0838/6/zh80140581360004.jpeg?Expires=1725040864&Signature=GzJzslfNHvK3RQODiQMn69An33NT4Tivrf-HhCv~hy0xwZZsHq5DQyLmqDjhLZ6Sa7KMxOZs1BWs4UdphxcUEm621M-WIpNbgeTnvWHUXIE2UKVHL9rAyyDWqX4PPKdZJpj-VVbqnX4s4-PHNIYgNUIOnFCeolZl8yYpvN-XyLvP7lYX24eSIhS~hxkrq3mTvK6764cN1aX3GuQ67PdDuH4KgAX3Gfg8GwTF2Wxq11Rh8Gh2VqVuYbgo5brWc4zfCg7QKWwbeFsnL4h6Pd-Q3e3wCQe~72O72rAQ4GWuAPUzc5mkD7Q2wnFn-VTmAg4E4ShN6QhTkPX2E8NmVqBeQw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
R-etodolac synergistically enhances Dex-induced cytotoxicity against MM cells. MM.1S cells were cultured for 24 hours with control media (□) and with 0.5 μM Dex (▦) or 1.0 μM Dex (▪) in the presence or absence of R-etodolac (0.15-0.6 mM). Cell growth was assessed by [3H]-thymidine uptake (A) and MTT assays (B). CPM indicates counts per minute. (C) Dose dependency for inhibition of proliferation of MM1.S cells at 24 hours was analyzed by MTT assays, after culture with 18 to 600 μM R-etodolac alone (♦), 0.06 to 2 μM Dex alone (□), or both (▴). Data represent mean (± SD) of quadruplicate cultures.
