Leukocyte-endothelial cell interactions. Numbers of leukocytes rolling (A) and adherent (B) in postsinusoidal venules as well as number of leukocytes intravascularly accumulated in sinusoids (C) were quantitatively analyzed using intravital video fluorescence microscopy in sham-operated mice, JAM-A^+/+ mice after I/R (I/R-JAM^+/+), JAM-A^-/- mice after I/R (I/R-JAM^-/-), and in endothelial JAM-A^-/- mice after I/R (I/R-eJAM^-/-). Ischemia time: 90 minutes; reperfusion time: 30 minutes (▪) and 120 minutes (□). n = 6 animals per group; mean ± SEM; ^*P < .05 versus sham-operated group; #P < .05 versus IR-JAM-A^+/+ group.