Figure 1.
Figure 1. Representative antibody response charts and binding patterns of mononuclear cells on the LD array. (A) Healthy individuals, (B) long-term nonprogressors, (C) first-line therapy, and (D) salvage therapy. The median and standard error of the mean of the binding intensity of each CD antigen is shown. Labeling on the x-axis refers to monoclonal antibodies with specificities against the corresponding CD antigens; TCRαβ, TCRγδ, HLA-DR, FMC-7, κ, λ, and sIg are monoclonal antibodies against T-cell receptors αβ and γδ, HLA-DR, FMC-7, kappa and lambda immunoglobulin light chains, and surface immunoglobulin, respectively. On the right of each histogram, corresponding dot plots demonstrate the binding patterns of mononuclear cells on the LD array. (E) The key for these CD antigens in the dot plot is as follows: boldface indicates T-cell markers; italics, B-cell markers; and underline, myeloid markers. Combinations of these indicate lineage origin. Others are left in normal font; stem cell markers were CD34 and CD117.

Representative antibody response charts and binding patterns of mononuclear cells on the LD array. (A) Healthy individuals, (B) long-term nonprogressors, (C) first-line therapy, and (D) salvage therapy. The median and standard error of the mean of the binding intensity of each CD antigen is shown. Labeling on the x-axis refers to monoclonal antibodies with specificities against the corresponding CD antigens; TCRαβ, TCRγδ, HLA-DR, FMC-7, κ, λ, and sIg are monoclonal antibodies against T-cell receptors αβ and γδ, HLA-DR, FMC-7, kappa and lambda immunoglobulin light chains, and surface immunoglobulin, respectively. On the right of each histogram, corresponding dot plots demonstrate the binding patterns of mononuclear cells on the LD array. (E) The key for these CD antigens in the dot plot is as follows: boldface indicates T-cell markers; italics, B-cell markers; and underline, myeloid markers. Combinations of these indicate lineage origin. Others are left in normal font; stem cell markers were CD34 and CD117.

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