Hematopoietic potential of Hex-deficient ES cells. (A-B) RT-PCR expression analysis of different staged serum-stimulated EBs generated from Hex^+/+ (+/+), Hex^+/- (+/-), and Hex^-/- (-/-) ES cells. (C) Hematopoietic progenitor analysis of Hex^+/+,Hex^+/-, and Hex^-/- EBs differentiated for 6 days. Numbers represent colonies per 1 × 10⁵ cells plated. Data represent means ± SEMs (n = 3). Ep indicates primitive erythroid colonies; MAC, macrophage colonies; MIX, large multilineage hematopoietic colonies consisting of macrophages, definitive erythroid cells, and neutrophils.