Figure 3.
![Figure 3. AZT-mediated apoptosis and phosphorylation in EBV+ BL cells is inhibited by p65. (A) Serially passaged BL-5R cells were treated with AZT (10 μg/mL) for 40 hours, and apoptosis was measured by FACS analysis. (B) BL-5 and BL-5R cells were treated with [methyl-3H]-AZT for 1, 4, 8, and 16 hours. Methanol extracts were subjected to HPLC analysis. The figure demonstrates the relative amounts of AZT-MP generated in each line. (C) AZT-resistant BL-5 cells (BL-5R) were analyzed for NF-κB subunit usage by supershift analysis. Results are shown as the mean ± standard deviation.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/106/1/10.1182_blood-2004-09-3748/4/zh80130580510003.jpeg?Expires=1724182577&Signature=oh3I2ublM075L~q4P72fakuAKm9ItcL4pfyhOy7Q9vaqWRY48kRbW0LqXCuoW3Wk~XIGnwhoE4fqm6uEQXKU1mv0XioU9oUpPSUvJjMZNZlQVHfGplBfjq0jE5NmYBfPK8hQFkcT-5gbvUnYk7nVu~qkfM7MZmdE2JoKJl~NLIa5F-hnUe5dPey5DdIh5VWDVvz~Qg4EAe7DA2kDAePgw5w4k6mSXILfhzMFzCqODnmD9zfQfbqcIVhxyU5HYvuN11aK0rHOE-gX6xTfGCq3Yf7Z1uJO6qkVlkfufiBoahf5DT~hpQ49-Q90iUfGotSmqpgbD2QYi6qEnUtiRCJo2w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
AZT-mediated apoptosis and phosphorylation in EBV+ BL cells is inhibited by p65. (A) Serially passaged BL-5R cells were treated with AZT (10 μg/mL) for 40 hours, and apoptosis was measured by FACS analysis. (B) BL-5 and BL-5R cells were treated with [methyl-3H]-AZT for 1, 4, 8, and 16 hours. Methanol extracts were subjected to HPLC analysis. The figure demonstrates the relative amounts of AZT-MP generated in each line. (C) AZT-resistant BL-5 cells (BL-5R) were analyzed for NF-κB subunit usage by supershift analysis. Results are shown as the mean ± standard deviation.
