Figure 1.
![Figure 1. Factor VII ratio and INR change according to VKORC1 genotype after a single oral dose of acenocoumarol. Factor VII ratio (A) corresponds to remaining factor VII, expressed as a percentage compared with baseline value, before AC intake (eg, [Factor VII 24 h after AC intake/Factor VII before AC intake] × 100). (B) INR change is expressed as the formula: (INR 24 h after AC intake – INR before AC intake/INR before AC intake) × 100. Bars represent means; factor VII ratio and INR change were significantly different between each intragroup. ***P < .01.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/106/1/10.1182_blood-2005-01-0341/4/zh80130580660001.jpeg?Expires=1722538848&Signature=v4UhAI-Cm5vbtlC7MdG1WvFwPFTwAX3jv31U7AQWU8n0VD2PdoFx1LkPgIzPrEOghOdm1DDqO6bCf~O3nKhfklWsV89Qt4UWw9CuDVrHlut8OZyEeK~kmcI2fLDOZ6NC-C6BLi188qcpJUztwdgaoinNonYc4eMcEubcqBGgOEcdDXSVcaPkQbDxE5l9tOrDjPYNJo8b-cJ3MKWA9WgJgRf~rhlr~TH5jH--D7RPWrWtLoo2Z9ypj-aJ-jZE7Mgm4Ltvm8hHbFv93bDpGDl~QW7dASVy9fo1Z2YGQesUElnj6HtSO44nGq65maZXVso3jr~abnidhKb9aXYdWlr1xg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Factor VII ratio and INR change according to VKORC1 genotype after a single oral dose of acenocoumarol. Factor VII ratio (A) corresponds to remaining factor VII, expressed as a percentage compared with baseline value, before AC intake (eg, [Factor VII 24 h after AC intake/Factor VII before AC intake] × 100). (B) INR change is expressed as the formula: (INR 24 h after AC intake – INR before AC intake/INR before AC intake) × 100. Bars represent means; factor VII ratio and INR change were significantly different between each intragroup. ***P < .01.
