Repair of oxidative and alkylating DNA damage in T-cell subsets during HIV infection. faPy DNA glycosylase activity (A-B) and alkylated base DNA glycosylase activity (C-D) in extracts of CD4⁺ and CD8⁺ T cells from HIV-infected patients and controls. Extracts isolated from AIDS patients (n = 7), HIV-infected patients (n = 8), and healthy controls (n = 13) were incubated with 0.4 μg 3H-labeled faPy-poly(dG-dC) DNA or alkylated calf thymus DNA. Horizontal lines represent median values.