Histologic results. Muscle and nerve histology in CHS patients 26 (patient 1) and 21 years (patient 3) after transplantation. (A-B) Muscle samples of patient 3 (A) and 1 (B) demonstrate areas of neurogenic atrophy of muscular fibers, which were more prominent in patient 3 (hematoxylin-eosin stain). (C-D) Semithin sections of samples from patient 3 demonstrate moderate rarefaction of large myelinated fibers, few remyelinated fibers, and endoneural macrophages containing dense osmiophilic inclusions (arrows in panel C; Toluidine blue stain). Images were visualized under a Laborlux 5 type 020505030 inverted microscope equipped with a dry periplan 10×/0.25 objective lens (Leitz, Portugal) and an Olympus OM-4T camera (Olympus, Melville, NY). Adobe Photoshop CS.8 software (Adobe, San Jose, CA) was used for image processing.