Figure 3.
Figure 3. Low ULBP and NCR ligand expression in AML. PB samples from AML patients were stained with mAbs against lineage-specific markers and anti-CD45 mAbs to distinguish CD45dim leukemic blasts from CD45bright residual normal monocytes and granulocytes. ULBP1, ULBP2, and ULBP3 (left column) were measured with specific mAbs on monocytes (⋄), granulocytes (○) and blasts (). Binding of sNKp30, sNKp44, and sNKp46 dimers (right column) to monocytes (⋄), granulocytes (○), and blasts (). Mean values are indicated as horizontal bars. *P < .05; **P < .005.

Low ULBP and NCR ligand expression in AML. PB samples from AML patients were stained with mAbs against lineage-specific markers and anti-CD45 mAbs to distinguish CD45dim leukemic blasts from CD45bright residual normal monocytes and granulocytes. ULBP1, ULBP2, and ULBP3 (left column) were measured with specific mAbs on monocytes (⋄), granulocytes (○) and blasts (). Binding of sNKp30, sNKp44, and sNKp46 dimers (right column) to monocytes (⋄), granulocytes (○), and blasts (). Mean values are indicated as horizontal bars. *P < .05; **P < .005.

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