Figure 5.
Figure 5. Normalization of hematopoietic progenitor cell formation in gp130Y757F/Y757F: Stat3+/- mice. In vitro hematopoietic colony formation of (A) bone marrow cells and (B) spleen cells from gp130+/+ (□), gp130Y757F/Y757F (▪), and gp130Y757F/Y757F: Stat3+/- (▦) mice in semisolid agar containing SCF (50 ng/mL) and IL-3 (10 ng/mL). Data from 4 to 6 mice of each genotype are expressed as the mean ± SD. *P < .05 versus data from gp130+/+ mice. G indicates granulocyte; GM, granulocyte/macrophage; M, macrophage; Eo, eosinophil; and Meg, megakaryocyte.

Normalization of hematopoietic progenitor cell formation in gp130Y757F/Y757F: Stat3+/- mice. In vitro hematopoietic colony formation of (A) bone marrow cells and (B) spleen cells from gp130+/+ (□), gp130Y757F/Y757F (▪), and gp130Y757F/Y757F: Stat3+/- (▦) mice in semisolid agar containing SCF (50 ng/mL) and IL-3 (10 ng/mL). Data from 4 to 6 mice of each genotype are expressed as the mean ± SD. *P < .05 versus data from gp130+/+ mice. G indicates granulocyte; GM, granulocyte/macrophage; M, macrophage; Eo, eosinophil; and Meg, megakaryocyte.

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