Reduced intestinal MCp reconstitution in SIBR mice by treatment with anti–MAdCAM-1 or anti–VCAM-1 and in VCAM-1^-/- mice. (A-B) Bars represent the intestinal MCp concentrations (A) and the absolute number of intestinal MCps (B) in SIBR mice reconstituted with wild-type BM cells and treated with saline or antibody (Ab) directed against the indicated endothelial ligands. Values are the mean ± SEM for 4 experiments. (C-D) Bars represent the intestinal MCp concentrations (C) and the absolute number of intestinal MCps (D) in VCAM-1Flox and in VCAM^-/- mice evaluated in parallel. Values are the mean ± SEM for 3 experiments.