Figure 5.
SKY analysis of cytogenetically aberrant clones L46 and L31.2. In this classified image, altered chromosome pairs are boxed. Translocated regions are marked with yellow numbers. In L46, a balanced translocation T(1E3-F;9C-D) was present. The karyotype is described as: 37-40, XY, T(1E3-F;9C-D)[11]. L31.2 showed a complex rearrangement involving chromosomes 4 and 11 as well as an additional chromosome 9 derived from an unbalanced translocation T(9B;18A2). The karyotype is described as: 38-40, XX, Der(4)T(4A2;11D), +Der(9)T(9B; 18A2), Der(11)T(11pter->11B3-?4::4A2-A3->4D3::11B3-4->11D::4A2-A3->4A1), -18[13]/40,XX [2.].