Figure 3.
Factor X activation by the extrinsic Xase (♦) and A23187-treated platelets (▪). Either treated platelets at 6 × 108/mL concentration (3 × mean physiologic) or 20 pM relipidated TF were incubated with 0.5 nM factor VIIa in the presence of 100 μM PCPS. Factor X (170 nM) was added and factor Xa generation was measured in a chromogenic assay.
