Treatment end points were rapidly reached in the MBMP group. Kaplan-Meier plots. (A) Median time to reduce inhibitor to undetectable levels, 3 days (95% CI, 2-4 days). (B) Median time of factor substitution, 12 days (95% CI, 7-17 days). (C) Median time of treatment, 14 days (95% CI, 11-17 days). Abscissa shows time in apheresis days. Numbers above the Kaplan-Meier curves represent patients concluding the MBMP within the corresponding time period. Vertical excursions of the curves signify the occurrence of events. Dotted line indicates the median.