Generation of kCYC^+/- transgenic mice using murine VEGFR-3 promoter. (A) Construct design used for generation of mice. (B) kCYC-specific mRNA expression by real-time RT-PCR using lung tissue from different founder lines. (C) Real-time RT-PCR for VEGFR3 (□, left y-axis) and kCYC (▪, right y-axis) mRNA in different tissues (mean ± SD, n = 5). LN, lymph node.