TPD52 expression in Hodgkin lymphoma. (A) Mixed cellularity Hodgkin lymphoma. Mononuclear variants show strong (arrow) and moderate (arrowhead) TPD52 positivity (original magnification × 800). (B-D) Tumor cell–rich Hodgkin lymphoma (original magnification × 400). A nodule of tumor cells (^*) that are CD30⁺ (not shown) and CD79a^- (B) displays nuclear staining for PAX5 (C) and cytoplasmic labeling for TPD52 (D). The rim of residual normal B cells at the periphery of the nodule served as positive control. Lymph node paraffin sections. The APAAP technique was used with hematoxylin counterstain.