Age regression coefficients and their 95% CIs estimated from linear models predicting level of inflammatory markers. Model “a” estimates the crude affect of age; model “b” is adjusted for cardiovascular risk factors; model “c” is also adjusted for subclinical cardiovascular diseases; and model “d” is adjusted for CHD, CHF, stroke, PAD, COPD, diabetes, hypertension, osteoporosis, CFR, cancer, dementia, and depression. R² values reported below the confidence interval are for the model used to estimate the age regression coefficients.