Comparison of cytokine secretion profile of anti-CD3– or TBI-conditioned recipients. (A) Survival of recipients conditioned with anti-CD3 (⬡) or TBI (—) after injection of donor TCD-BM (2 × 10⁶) and CD8⁺ T cells (20 × 10⁶). ▾ indicates recipients of TBI alone. There were 8 mice in each group. (B-E) TNF-α, IFN-γ, IL-4, and IL-10 in serum and culture supernatant (anti-CD3, ▪; TBI, □) of recipients from the 2 groups. Values are the mean ± SE of individual recipients in each group (n = 8). SPL indicates spleen.