Figure 1.
![Figure 1. Effects of perforin- or FasL-deficient CD8+ T cells on acute GVHD. Lethally irradiated bm1 mice received transplants as described in “Materials and methods” from wt B6 (wt), perforin-deficient B6 (pfp–/–), or Fas ligand–deficient B6 (gld) donors. Syngeneic B6 BM transplant recipients (syn) served as no-GVHD controls. At 30 days after BMT, liver and intestine (bottom column [•], small intestine; upper column, large intestine) were harvested and scored semiquantitatively (n = 4 mice/group). Data represent mean ± SD.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/105/5/10.1182_blood-2004-08-3036/6/zh80050574970001.jpeg?Expires=1724236831&Signature=eKZcWjQyS7JKo9fvKs5C3-UoNVCNuevfZOoyZxuQLCgbZOF0n7cH5DFzOVtqOMYZ6yAElWRae6cCpGbg-A13rAJTMrNnG9TlHpfdpHhtUckIJlJpwx8ryhGi5i4xNNU4eGTQwgy9jIKwUaxdFN6cQVgZxtTNcMcKaStWH3gjMJHIBEqBagjFq0yeBS2~skfr7CApfcAYrQMbUNIhXOnuVxKhqTp1Tym-P35t-CvyQa8b0Sgf4B-VvtbPOk2FyswJmRmAAv8JjhdYEfTFtPpuTH7RVYPEenTBaox-kdWmfxAyoLbdJe3xtKySG8KDvzae0V71KemYL96nXgTtoKbD2A__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effects of perforin- or FasL-deficient CD8+T cells on acute GVHD. Lethally irradiated bm1 mice received transplants as described in “Materials and methods” from wt B6 (wt), perforin-deficient B6 (pfp–/–), or Fas ligand–deficient B6 (gld) donors. Syngeneic B6 BM transplant recipients (syn) served as no-GVHD controls. At 30 days after BMT, liver and intestine (bottom column [•], small intestine; upper column, large intestine) were harvested and scored semiquantitatively (n = 4 mice/group). Data represent mean ± SD.
