Figure 3.
Figure 3. Erythrocyte reconstitution in vivo. Host erythropoiesis was transiently suppressed by irradiation (850 rad; split dose). After irradiation, mice were given intravenous injections of PBS (number of recipients [n] = 2; A), total BM (2 × 105 cells/mouse; n = 2; B), HSC (2500 cells/mouse; n = 2; C), CMP IL-3Rα– cells (5000 cells/mouse; n = 2; D), EPs (5000 cells/mouse; n = 2; E), MP1 (5000 cells/mouse; n = 1; F), CMP IL-3Rα+ (5000 cells/mouse; n = 2; G), GMP (5000 cells/mouse; n = 2; H), or MP2 (5000 cells/mouse; n = 1; I). Percentages of reticulocytes in peripheral blood were determined at the indicated time points. Data shown are representative for one of 2 experiments.

Erythrocyte reconstitution in vivo. Host erythropoiesis was transiently suppressed by irradiation (850 rad; split dose). After irradiation, mice were given intravenous injections of PBS (number of recipients [n] = 2; A), total BM (2 × 105 cells/mouse; n = 2; B), HSC (2500 cells/mouse; n = 2; C), CMP IL-3Rα cells (5000 cells/mouse; n = 2; D), EPs (5000 cells/mouse; n = 2; E), MP1 (5000 cells/mouse; n = 1; F), CMP IL-3Rα+ (5000 cells/mouse; n = 2; G), GMP (5000 cells/mouse; n = 2; H), or MP2 (5000 cells/mouse; n = 1; I). Percentages of reticulocytes in peripheral blood were determined at the indicated time points. Data shown are representative for one of 2 experiments.

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