Relationship of consensus clusters to cell-of-origin (COO) signature. Comparison of study DLBCLs sorted into consensus clusters with the same tumors classified by COO. The lack of a clear correlation between the 2 clustering systems is reflected by the absence of a matrix diagonal structure (ie, large numbers along the diagonal and numbers close to 0 in the off-diagonal entries). CTOT indicates total number of tumors in a row.