Figure 5.
Figure 5. Summary of proliferative responses to RhD autoantigen peptides by PBMCs from Patients with CLL with AIHA. ▪ indicates proportion of D-positive Patients with CLL with secondary AIHA (n = 8) whose PBMCs proliferate in response to peptides spanning the RhD protein. □ indicates results of parallel studies17 to map RhD peptides that stimulate PBMCs from patients with patients with primary AIHA patients (n = 11). The peptide panel is reduced to the 42 sequences with less overlap used in the previous work17 and is numbered accordingly. There is a significant correlation (Rs = 0.55; P < .0001) between the abilities of each RhD peptide to elicit proliferative responses in patients with primary and secondary AIHA.

Summary of proliferative responses to RhD autoantigen peptides by PBMCs from Patients with CLL with AIHA. ▪ indicates proportion of D-positive Patients with CLL with secondary AIHA (n = 8) whose PBMCs proliferate in response to peptides spanning the RhD protein. □ indicates results of parallel studies17  to map RhD peptides that stimulate PBMCs from patients with patients with primary AIHA patients (n = 11). The peptide panel is reduced to the 42 sequences with less overlap used in the previous work17  and is numbered accordingly. There is a significant correlation (Rs = 0.55; P < .0001) between the abilities of each RhD peptide to elicit proliferative responses in patients with primary and secondary AIHA.

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