Antigen-primed T cells maintain normal hematopoiesis. (A) Analyses of peripheral blood (left) and bone marrow (right) in WT (□), DO11.10 (▪), and DO11.10 RAG^–/– (▦) TCR transgenic mice. (B-D) TCR transgenic mice received 10 mg OVA intravenously (DO11.10 RAG^–/– + OVA). After 14 days the animals were killed and hematopoietic analysis was performed. (B) Morphologic analyses of WT (□) and OVA-treated (▪) mice peripheral blood (left) and bone marrow (right). Error bars mean SEM. (C) Flow cytometry analysis of OVA-challenged TCR transgenic mice. Dot plots are representative of SCA-1 × CD11b staining. Gates show CD11b⁺SCA-1⁺ population, and respective mean ± SD are indicated. (D) CD69 expression in bone marrow transgenic T cells. *P < .001; **P < .05; (n = 2-5).