Neutrophil adhesion induced by angiopoietins: implication of Tie2 receptors on HUVECs and neutrophils. HUVECs (left) or neutrophils (right) were pretreated for 15 minutes with blocking anti-hTie2 IgG (0.05 to 1 μg/mL) prior to stimulation with Ang1 (A), Ang2 (B), or the Ang1/Ang2 combination (10^–9 M; 7.5 minutes; C). Data are means ± SEM of at least 8 experiments; *P = .01 compared with PBS, §P = .01 compared with corresponding agonist.