Figure 6.
![Figure 6. Role of IL-10 and TGF-β in suppression mediated by T(imm) cells. (A) After 3 rounds of activation with immature DCs, T(imm) cells were tested for their ability to suppress the proliferation of CD4+ T cells in response to mature DCs, in the absence or presence of anti–IL-10R (30 μg/mL) and anti–TGF-β (50 μg/mL) mAbs. (B) Similar experiments were performed to assess the suppression of IFN-γ production by CD4+ T cells in response to mature DCs. (C) In parallel, proliferation and suppression in response to allogeneic monocytes was tested. [3H]-Thymidine was added at the indicated time for an additional 16 hours. Results are representative of 3 independent experiments.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/105/3/10.1182_blood-2004-03-1211/6/zh80030573190006.jpeg?Expires=1724253008&Signature=jBU7P5ERzimN2I~uwylxuJPk0AYIblKwLurpGU4pJHDl3kGB2I6AxRpn0hNZUy2NhFdTlDAwpvUcKFIax660MxKCF1w1nOGp1OR9HIMVD0du~4C2~ByRa~QyTeP-lSsOrWRxuiQRChIJy8PYLvbxoR-W-~9XDtyKNtiMEmR5~A4h8sQVBx3l5geYbGhOVZEChAY11xPRWcp~yMQzlM1zkhdxKzbzwtp2uIHLQVjZFGtjd3Nm7L3pOM8CvkjgWR9LgueomBQfqwiI9u3Ip~jpA9Ms4~4nz2xFFqsbw-XmXKD5S9nUIU8ybXyBHjJ5U7ExvXNmimdgPO~NKjRJkJUrsw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Role of IL-10 and TGF-β in suppression mediated by T(imm) cells. (A) After 3 rounds of activation with immature DCs, T(imm) cells were tested for their ability to suppress the proliferation of CD4+ T cells in response to mature DCs, in the absence or presence of anti–IL-10R (30 μg/mL) and anti–TGF-β (50 μg/mL) mAbs. (B) Similar experiments were performed to assess the suppression of IFN-γ production by CD4+ T cells in response to mature DCs. (C) In parallel, proliferation and suppression in response to allogeneic monocytes was tested. [3H]-Thymidine was added at the indicated time for an additional 16 hours. Results are representative of 3 independent experiments.
