Interaction of angiostatin with leukocyte integrins. Adhesion of PMA-stimulated THP-1 cells to immobilized K1-4 (A), K1-3 (B), or K4 (C) is shown in the absence (–) or presence of inhibitory mAb (each 20 μg/mL) as well as EACA (10 mM) as indicated. Cell adhesion is represented as absorbance at 590 nm. Data are mean ± SD (n = 3) of a typical experiment; similar results were obtained in 3 separate experiments.